Compare/Qwen2.5 Instruct 72B vs GPT-5.4 nano (medium)

Qwen2.5 Instruct 72BvsGPT-5.4 nano (medium)

Side-by-side comparison of pricing, 12 benchmarks, and generation speed.

Alibaba

Qwen2.5 Instruct 72B

Input
$0/M
Output
$0/M
Speed
56 tok/s
TTFT
1.05s
OpenAI

GPT-5.4 nano (medium)

Input
$0.2/M
Output
$1.25/M
Speed
171 tok/s
TTFT
2.38s

Winner by Category

Cheaper
Qwen2.5 Instruct 72B
Faster (tok/s)
GPT-5.4 nano (medium)
Lower Latency
Qwen2.5 Instruct 72B
Benchmarks (5-7)
GPT-5.4 nano (medium)

Pricing Comparison

MetricQwen2.5 Instruct 72BGPT-5.4 nano (medium)
Input ($/M tokens)$0$0.2
Output ($/M tokens)$0$1.25
Cost for 1M input + 100K output tokens:
Qwen2.5 Instruct 72B$0.00
GPT-5.4 nano (medium)$0.33

Speed Comparison

Output Speed (tokens/s) — higher is better
Qwen2.5 Instruct 72B
56 tok/s
GPT-5.4 nano (medium)
171 tok/s
Time to First Token (seconds) — lower is better
Qwen2.5 Instruct 72B
1.05s
GPT-5.4 nano (medium)
2.38s

Benchmark Comparison

Data from Artificial Analysis API — 12 benchmarks

Intelligence Index
15.638.1
Coding Index
11.935.0
Math Index
14.0
GPQA Diamond
49.1%76.1%
MMLU-Pro
72.0%
LiveCodeBench
27.6%
AIME 2025
14.0%
MATH-500
85.8%
Humanity's Last Exam
4.2%14.7%
SciCode
26.7%38.4%
IFBench
36.9%64.4%
TerminalBench
4.5%33.3%
Qwen2.5 Instruct 72B5 wins
7 winsGPT-5.4 nano (medium)

Frequently Asked Questions

Which is cheaper, Qwen2.5 Instruct 72B or GPT-5.4 nano (medium)?

Qwen2.5 Instruct 72B is cheaper overall. Its blended price (3:1 input/output ratio) is $0.00/M tokens vs $0.46/M for GPT-5.4 nano (medium).

Which model performs better on benchmarks?

GPT-5.4 nano (medium) wins 7 out of 12 benchmarks compared to 5 for Qwen2.5 Instruct 72B. See the detailed benchmark chart above for per-category results.

Which is faster for real-time applications?

GPT-5.4 nano (medium) generates tokens faster at 171 tok/s vs 56 tok/s. Qwen2.5 Instruct 72B also has lower time-to-first-token (1.05s vs 2.38s).

When should I use Qwen2.5 Instruct 72B vs GPT-5.4 nano (medium)?

Choose based on your priorities: Qwen2.5 Instruct 72B for lower cost, GPT-5.4 nano (medium) for stronger benchmark performance, and GPT-5.4 nano (medium) for faster generation. For latency-sensitive apps, check the TTFT comparison above.